翻訳と辞書 Words near each other ・ Tubulella ・ Tubuli seminiferi recti ・ Tubulicium ・ Tubulicrinis ・ Tubulin ・ Tubulin beta-4A chain ・ Tubulin beta-4B chain ・ Tubulin domain ・ Tubulin GTPase ・ Tubulinea ・ Tubulinyl-Tyr carboxypeptidase ・ Tubulin—tyrosine ligase ・ Tubuliporina ・ Tubullela ・ Tubulocystic renal cell carcinoma ・ Tubuloglomerular feedback ・ Tubulointerstitial nephritis and uveitis ・ Tubulopathy ・ Tubulovillous adenoma ・ Tubunae ・ Tubungan, Iloilo ・ Tuburan ・ Tuburan, Basilan ・ Tuburan, Cebu ・ Tubutama ・ Tubutama (municipality) ・ Tubutulik River ・ Tubądzin ・ TUC ・ TUC (cracker) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Tubuloglomerular feedback ： ウィキペディア英語版 Tubuloglomerular feedback In the physiology of the kidney, tubuloglomerular feedback (TGF) is one of several mechanisms the kidney uses to regulate glomerular filtration rate (GFR). It involves the concept of purinergic signaling, in which an increased distal tubular sodium chloride concentration causes a basolateral release of ATP from the macula densa cells. This initiates a cascade of events that ultimately brings GFR to an appropriate level. ==Background== Normal renal function requires that the flow through the nephron is kept within a narrow range. When tubular flow (that is, GFR) lies outside this range, the ability of the nephron to maintain solute and water balance is compromised. Additionally, changes in GFR may result from changes in renal blood flow (RBF), which itself must be maintained within narrow limits. Elevated RBF may damage the glomerulus, while diminished RBF may deprive the kidney of oxygen. Tubuloglomerular feedback provides a mechanism by which changes in GFR can be detected and rapidly corrected for on a minute-to-minute basis as well as over sustained periods. Regulation of GFR requires both a mechanism of detecting an inappropriate GFR as well as an effector mechanism that corrects it. The macula densa serves as the detector, while the glomerulus acts as the effector. When the macula densa detects an elevated GFR, it releases several molecules that cause the glomerulus to rapidly decrease its filtration rate. (Technically, the macula densa detects a SNGFR, single nephron GFR, but ''GFR'' is used here for simplicity.) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Tubuloglomerular feedback」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.